Alkaloids Identified in Kratom

Alkaloids identified in Kratom Mitragyna Speciosa

Concentration percentages given come from different studies of alkaloid concentrations in Mitragyna speciosa, thr Kratom leaf. Some of the alkaloids in the list below still need to be studied in more detail to determine their potential activity.

  • Ajmalicine (Raubasine): Cerebrocirculant, antiaggregant, anti-adrenergic (at alpha-1), sedative, anticonvulsant, smooth muscle relaxer. Also found in Rauwolfia serpentina.
  • Akuammigine
  • Ciliaphylline: antitussive, analgesic. < 1% of total alkaloid content found in Kratom leaf.
  • Corynantheidine: μ -opioid antagonist, also found in Yohimbe. < 1% of total alkaloid content found in Kratom leaf.
  • Corynoxeine: Calcium channel blocker.
Botany and Kratom Mitragyna Speciosa

Botany and Kratom Mitragyna Speciosa

The vernacular term Kratom refers to the Mitragyna Speciosa var. Korthals tree and the products derived from its leaves, which concentrate the plant’s active principles. The botanical classification of Mitragyna Speciosa Kratom is as follows:

Division: Magnoliophyta
Class: Magnoliopsida
Order: Gentianales
Family: Rubiaceae
Genus: Mitragyna
Species: M. Speciosa

The Mitragyna Speciosa Kratom tree is in the Rubiaceae botanical family, a genus that includes many well know and useful psychoactive plants such as the Coffee tree (Coffea),